Module 5 is taught by Nicolai Loboda and covers the cellular and molecular mechanisms of wound healing, pain pathways, sensory neurology, and the emerging field of resoleomics (the active resolution of inflammation through specialized pro-resolving mediators).
The module integrates immune system resolution mechanisms, nociceptive and neuropathic pain pathways, the role of specialized pro-resolving mediators (SPMs) in tissue repair, and clinical applications for managing chronic pain and delayed healing. It emphasizes the transition from inflammatory to resolution phases as an active, regulated process requiring specific mediators and receptors.
This module provides essential knowledge for clinical management of chronic pain, non-healing wounds, and inflammatory conditions. Understanding resoleomics offers therapeutic strategies beyond anti-inflammation, focusing on enhancing endogenous resolution mechanisms through nutrition (omega-3s), lifestyle, and targeted interventions.